Galen Hostetter Selected Research

Neoplasms (Cancer)

1/2021	Impact of Preanalytical Factors on the Measurement of Tumor Tissue Biomarkers Using Immunohistochemistry.
1/2021	A proteogenomic portrait of lung squamous cell carcinoma.
10/2020	Loss of microRNA-21 leads to profound stromal remodeling and short survival in K-Ras-driven mouse models of pancreatic cancer.
1/2020	Lgr5-positive endothelial progenitor cells occupy a tumor and injury prone niche in the kidney vasa recta.
11/2019	Ductal tree ablation by local delivery of ethanol prevents tumor formation in an aggressive mouse model of breast cancer.
1/2019	Characterization of farnesyl diphosphate farnesyl transferase 1 (FDFT1) expression in cancer.
1/2018	Nuclear PTEN Localization Contributes to DNA Damage Response in Endometrial Adenocarcinoma and Could Have a Diagnostic Benefit for Therapeutic Management of the Disease.
1/2017	Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer.
1/2017	The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells.
11/2016	Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.

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Galen Hostetter Research Topics

Disease

48	Neoplasms (Cancer) 01/2021 - 03/2002
19	Pancreatic Neoplasms (Pancreatic Cancer) 01/2017 - 09/2003
7	Carcinogenesis 01/2019 - 07/2007
7	Adenocarcinoma 01/2017 - 10/2009
5	Breast Neoplasms (Breast Cancer) 11/2019 - 01/2012
4	Neoplasm Metastasis (Metastasis) 08/2015 - 01/2008
3	Carcinoma (Carcinomatosis) 10/2015 - 05/2007
2	Prostatic Neoplasms (Prostate Cancer) 10/2015 - 03/2002
2	Fibrosis (Cirrhosis) 10/2015 - 08/2015
2	Colorectal Neoplasms (Colorectal Cancer) 06/2014 - 09/2003
2	Hypoxia (Hypoxemia) 06/2013 - 07/2010
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2012 - 10/2010
2	Glioma (Gliomas) 11/2009 - 10/2006
1	Inflammation (Inflammations) 11/2022
1	Ewing Sarcoma (Sarcoma, Ewing) 11/2016
1	Cysts 01/2016
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 10/2015
1	Triple Negative Breast Neoplasms 12/2014
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2012
1	Adenoma (Adenomas) 01/2012
1	Adrenal Cortex Neoplasms (Adrenocortical Cancer) 01/2012
1	Adrenocortical Carcinoma 01/2012
1	Melanoma (Melanoma, Malignant) 10/2010
1	Actinic Keratosis 10/2010

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 01/2019 - 03/2002
11	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2005
8	DNA (Deoxyribonucleic Acid)IBA 06/2014 - 09/2008
7	Messenger RNA (mRNA)IBA 01/2019 - 03/2002
7	Small Interfering RNA (siRNA)IBA 01/2012 - 10/2006
5	LigandsIBA 11/2022 - 09/2008
4	Phenobarbital (Luminal)FDA Link 01/2018 - 03/2013
4	Polysaccharides (Glycans)IBA 01/2017 - 05/2015
3	EnzymesIBA 01/2019 - 09/2003
3	sulfhydryl oxidaseIBA 01/2018 - 12/2011
3	Pharmaceutical PreparationsIBA 01/2017 - 01/2012
3	Transcription Factors (Transcription Factor)IBA 11/2016 - 07/2010
3	Estrogen ReceptorsIBA 12/2014 - 04/2012
3	NF-kappa B (NF-kB)IBA 01/2012 - 10/2006
3	OligonucleotidesIBA 01/2012 - 01/2008
3	Peptides (Polypeptides)IBA 12/2011 - 10/2009
3	Complementary DNA (cDNA)IBA 01/2008 - 03/2002
2	Formaldehyde (Formol)FDA Link 01/2021 - 01/2010
2	SurvivinIBA 01/2021 - 01/2021
2	AntigensIBA 01/2021 - 01/2017
2	LipidsIBA 01/2019 - 07/2007
2	Phosphotransferases (Kinase)IBA 01/2017 - 07/2007
2	CollagenIBA 01/2017 - 08/2015
2	Hyaluronic Acid (Hyaluronan)IBA 08/2015 - 09/2011
2	Sialyl Lewis X AntigenIBA 06/2015 - 05/2015
2	CA-19-9 Antigen (CA 19-9 Antigen)IBA 06/2015 - 05/2015
2	ErbB Receptors (EGF Receptor)IBA 12/2014 - 07/2012
2	RNA (Ribonucleic Acid)IBA 03/2013 - 12/2011
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 07/2012 - 10/2006
2	AgarIBA 01/2012 - 11/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2009 - 10/2006
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2007 - 09/2005
1	ChemokinesIBA 11/2022
1	ChromatinIBA 01/2021
1	leucine receptorIBA 01/2020
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2020
1	Ethanol (Ethyl Alcohol)IBA 11/2019
1	farnesyl pyrophosphate (farnesyl diphosphate)IBA 01/2019
1	TransferasesIBA 01/2019
1	fasudil (AT 877)IBA 01/2017
1	CarbohydratesIBA 01/2017
1	PM 01183IBA 11/2016
1	Irinotecan (Camptosar)FDA LinkGeneric 11/2016
1	EWS-FLI fusion proteinIBA 11/2016
1	Oncogene Proteins (Oncogene Protein)IBA 11/2016
1	OligosaccharidesIBA 01/2016
1	AcetylglucosamineIBA 01/2016
1	hepsinIBA 10/2015
1	CateninsIBA 10/2015
1	LectinsIBA 06/2015
1	FucoseIBA 06/2015
1	Complement System Proteins (Complement)IBA 06/2015
1	AntibodiesIBA 05/2015
1	human ERBB2 proteinIBA 12/2014
1	Progesterone Receptors (Progesterone Receptor)IBA 12/2014
1	Complex MixturesIBA 12/2014
1	mirdametinibIBA 01/2014
1	GelatinIBA 03/2013
1	Antineoplastic Agents (Antineoplastics)IBA 01/2013
1	Cell Surface ReceptorsIBA 01/2013
1	Zinc Finger Protein Gli2IBA 05/2012
1	Mitotane (Lysodren)FDA Link 01/2012
1	Biological ProductsIBA 01/2012
1	Albumin-Bound Paclitaxel FDA Link 01/2012
1	130-nm albumin-bound paclitaxelIBA 01/2012
1	Matrix Metalloproteinases (MMPs)IBA 12/2011
1	matrigelIBA 12/2011
1	Indicators and Reagents (Reagents)IBA 09/2011
1	Hyaluronoglucosaminidase (Hyaluronidase)FDA Link 09/2011
1	Eukaryotic Initiation Factor-4EIBA 10/2010

Therapy/Procedure

12	Therapeutics 11/2016 - 09/2003
4	Drug Therapy (Chemotherapy) 01/2018 - 11/2009
3	Radiotherapy 01/2018 - 11/2009
1	Isogeneic Transplantation 10/2020
1	Prophylactic Mastectomy 11/2019
1	Pancreaticoduodenectomy 01/2012